What causes the excessive collagen formation in keloid scars?

Excessive collagen formation in keloid scars is primarily caused by an abnormal healing response. When the skin is injured, the body's natural healing process involves the production of collagen to repair the damaged area. In individuals prone to keloids, this process becomes dysregulated, leading to an overproduction of collagen that exceeds what is necessary for normal wound healing.

This abnormal response can result from various factors, such as the individual's skin type, the location and depth of the injury, and even the nature of the injury itself (for example, surgery, burns, or acne). The resulting keloid extends beyond the original site of injury, taking on a raised and thickened appearance. By understanding that the root cause lies in this abnormal healing response, practitioners can better address keloid formations and consider appropriate treatment options.